Preheat your grill or stovetop grill pan to medium-high heat.
In a large bowl, combine the ground chicken, chipotle peppers, garlic powder, onion powder, smoked paprika, sea salt, and black pepper. Mix thoroughly until all the ingredients are well incorporated.
Divide the mixture into four equal parts and form each into a patty about 3/4 inch thick.
Brush each patty lightly with olive oil to prevent sticking to the grill.
Place the patties on the hot grill and cook for about 6-7 minutes on each side or until the internal temperature reaches 165°F (74°C) and the juices run clear.
In the last couple of minutes of cooking, sprinkle the shredded cheddar cheese on top of each burger to melt.
While the burgers are cooking, prepare the lettuce leaves, avocado slices, and any other desired toppings.
Once cooked, let the burgers rest for a few minutes before assembling.
Spread mayonnaise on each lettuce leaf, add the cooked burger, top with avocado slices, and any additional toppings you've chosen.
Serve immediately and enjoy your spicy, smoky, and utterly delicious keto-friendly chicken burgers.